Author Archives: lecao

Independent Principal Component Analysis (IPCA) In some case studies, we have identified some limitations when using PCA: PCA assumes that gene expression follows a multivariate normal distribution and recent studies have demonstrated that microarray gene expression measurements follow instead a … Continue reading →

A multilevel approach has been added for cross-over design experiments (up to two cross factors), in collaboration with A/Prof B. Liquet (Universite de Bordeaux, France).  This approach takes into account the complex structure of repeated measurements from different assays, where different treatments are applied … Continue reading →