sPCA Multidrug Case Study

The R script used for all the analysis in this case study is available here.

For background information on the (s)PCA method, refer to the PCA Methods Page.

More information on Plots

For a more in depth explanation of how to use and interpret the plots seen, refer to the following pages:

• plotIndiv() – Sample Plot
• plotVar() – Correlation Circle Plot
• biplot() – Biplot

References

1. Szakács G., Annereau J.-P., Lababidi S., Shankavaram U., Arciello A., Bussey K.J., Reinhold W., Guo Y., Kruh G.D., Reimers M., Weinstein J.N. and Gottesman M.M. (2004) Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells. Cancer Cell 4, pp 147-166.