Multiblock sPLS Gastrulation (Single Cell) Case Study

For background information on the (s)PLS or N-integrative methods, refer to the Multiblock PLS Methods Page and the N-integration Methods Page.

The R script used for all the analysis in this case study is available here.

 

More information on Plots

For a more in depth explanation of how to use and interpret the plots seen, refer to the following pages:

• plotIndiv() – Sample Plot
• plotArrow() – Arrow Plot
• plotVar() – Correlation Circle Plot
• circosPlot() – Circos Plot

More information

For more details on how to construct a design matrix see N-integration methods.

References

Argelaguet, R., Clark, S.J., Mohammed, H. et al. Multi-omics profiling of mouse gastrulation at single-cell resolution. Nature 576, 487–491 (2019). https://doi.org/10.1038/s41586-019-1825-8