Case Study
For a more in depth breakdown of the functionality and usage of these functions, refer to Case Study: MINT Stem Cells.
Further Reading
The mixOmics
MINT methodology has been applied in real research contexts. A few examples can be seen below:
- Poirier S, Déjean, S, Midoux, C, Lê Cao K-A, Chapleur O (2020). Integrating independent microbial studies to build predictive models of anaerobic digestion inhibition by ammonia and phenol. Bioresource Technology 316:123952
- Tian L, Dong X, Freytag S, Lê Cao K-A, Su S, Abadi AJ, Amann-Zalcenstein D, Weber TS, Seidi S, Jabbari JS, Naik S, Ritchie ME (2019). Benchmarking single cell RNA-sequencing analysis pipelines using mixture control experiments. Nature methods. Jun;16(6):479-487
References
- Rohart, F., Mason, E. A., Matigian, N., Mosbergen, R., Korn, O., Chen, T., Butcher, S., Patel, J., Atkinson, K., Khosrotehrani, K., Fisk, N. M., Lê Cao, K., and Wells, C. A. (2016). A molecular classification of human mesenchymal stromal cells. PeerJ, 4, e1845.
- Rohart, F., Eslami, A., Matigian, N. et al. MINT: a multivariate integrative method to identify reproducible molecular signatures across independent experiments and platforms. BMC Bioinformatics 18, 128 (2017). https://doi.org/10.1186/s12859-017-1553-8.