Author Archives: klecao

Φ-Space: Continuous phenotyping of single-cell multi-omics data

Posted on June 24, 2024 by klecao

We have developed a new PLS method for cell type continuous annotation of single cells, now in preprint! Φ-Space addresses numerous challenges faced by state-of-the-art automated annotation methods: to identify continuous and out-of-reference cell states, to deal with batch effects … Continue reading →

Posted in Methods, Publications, Updates, webinar | Comments Off

PCA and PLS-DA

Posted on June 5, 2024 by klecao

These two recordings were part of a presentation to WEHI for their postgraduate lecture series for a diverse audience. In the PCA presentation (18 min), we explain the concept of linear combination of variables (components) and useful graphical outputs such … Continue reading →

Posted in Graphics, Methods, webinar | Tagged PCA, PLSDA, webinar | Comments Off

[open] Self-paced online course Oct 21 – Dec 6 2024

Posted on June 5, 2024 by klecao

Feedback from a previous iteration can be found here. Key summary The new course is open and will run for 7 weeks. This course is online, but at your own pace, meaning that you need to dedicate enough time (5-8h per week) to fully … Continue reading →

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Microbial network inference for longitudinal microbiome studies with LUPINE

Posted on May 17, 2024 by klecao

Our latest method based on PLS to infer microbial networks across time is now in preprint! LUPINE is a PLS-based method that combines dimension reduction, and partial correlations to infer associations between taxa. LUPINE takes into account information across time … Continue reading →

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[closed] Self-paced online course Feb 5 – March 22 2024

Posted on October 9, 2023 by klecao

This workshop is now closed. Fill in this short survey to register your interest. A new iteration of the course might be run between Sept – Nov if there is sufficient interest! Key summary The new course is open and … Continue reading →

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[closed] Self-paced online course May 22 – July 7 2023

Posted on March 19, 2023 by klecao

If you’ve missed out, our next iteration will run from 19th Feb – 5th April 2024. You can fill up this short survey to be notified when we open our next course. Some feedback from 2023 Summary The new course … Continue reading →

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[closed] 13-14 March 2023, Brisbane, Aus

Posted on January 13, 2023 by klecao

We will be running a 2-day workshop at Frazer Institute, University of Queendland. The workshop will cover 1.5 days of lectures and hands-on, and an additional 0.5 day for discussions and opportunities to analyse your own data (assuming the data … Continue reading →

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[Closed] Self-paced online course Oct 31st – Nov 27 2022

Posted on August 13, 2022 by klecao

The next iteration of the course will be in September 2023 for a likely duration of 6-8 weeks (it will be advertised 3 months before opening the course). This course is online, but at your own pace, meaning that you … Continue reading →

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Our book is out!

Posted on November 8, 2021 by klecao

We are excited to announce that our book is out, along with several case studies and R scripts available online. Check out this page. It’s been a very (very) long term project, and a great collaboration with Zoe Welham whose … Continue reading →

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[Closed] Self paced online course Oct 11 – Nov 7 2021

Posted on September 19, 2021 by klecao

Our next round of online learning will be 31st October 2022! Some feedback from this course: Overall, this was a great course to take and I wish there would be more stats courses for biologists. Kim Anh is truly an … Continue reading →